Rapid Progressive Subacute Sclerosing Panencephalitis in a 2-Year-Old Child with Congenital Athyreosis | Zendy

Gerd-Michael Lackmann | Zendy; M. Hannen | Zendy; Faramarz Madjlessi | Zendy; H. G. Lenard | Zendy; Horst Schroten | Zendy

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Rapid Progressive Subacute Sclerosing Panencephalitis in a 2-Year-Old Child with Congenital Athyreosis

Author(s) -

Gerd-Michael Lackmann,

M. Hannen,

Faramarz Madjlessi,

H. G. Lenard,

Horst Schroten

Publication year - 2000

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/313917

Subject(s) - subacute sclerosing panencephalitis , medicine , measles , measles virus , girl , pediatrics , viral disease , virus , disease , immunology , pathology , vaccination , psychology , developmental psychology

We present the unique case of a 2-year-old girl with congenital athyreosis who acquired primary measles virus infection at the age of 18 months, coincidentally with an Epstein-Barr virus infection. First neurologic symptoms of subacute sclerosing panencephalitis appeared 5 months later, and the girl died within 6 months after a rapid progressive illness. Factors possibly predisposing to this extraordinary disease course-primary measles virus infection at an early age and lack of evidence for immunodeficiency-are discussed.

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