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Recurrent Blastomycosis of the Central Nervous System: Case Report and Review
Author(s) -
Ashish Chowfin,
Robert R. Tight,
S. L. Mitchell
Publication year - 2000
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/313828
Subject(s) - blastomycosis , medicine , amphotericin b , central nervous system , surgery , dermatology , antifungal
Although blastomycosis of the central nervous system (CNS) occurs in approximately 4% of patients with blastomycosis, recurrent CNS blastomycosis is very rare. We review the clinical features, treatment, and outcome of 4 previously reported cases. We also report a case of recurrent CNS blastomycosis successfully treated with surgery and liposomal amphotericin B after an inadequate response to amphotericin B therapy. This treatment may be an alternate approach for management of similar cases.

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