The Relation between Chlamydia pneumoniae Infection and Abdominal Aortic Aneurysm: Case-Control Study | Zendy

James Blanchard | Zendy; Haroutune K. Armenian | Zendy; Rosanna W. Peeling | Zendy; P. P. Friesen | Zendy; Caixia Shen | Zendy; Robert C. Brunham | Zendy

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The Relation between Chlamydia pneumoniae Infection and Abdominal Aortic Aneurysm: Case-Control Study

Author(s) -

James Blanchard,

Haroutune K. Armenian,

Rosanna W. Peeling,

P. P. Friesen,

Caixia Shen,

Robert C. Brunham

Publication year - 2000

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/313806

Subject(s) - medicine , abdominal aortic aneurysm , chlamydia , chlamydophila pneumoniae , serology , pathogenesis , odds ratio , chlamydiaceae , aneurysm , aortic aneurysm , immunology , antibody , abdominal aorta , chlamydiales , aorta , surgery

Due to recent interest in the role of Chlamydia pneumoniae as a pathogen of the vascular system, a case-control study was conducted to investigate the association between serological evidence of infection with C. pneumoniae and the occurrence of abdominal aortic aneurysm. Detectable IgG antibody to C. pneumoniae was more common among abdominal aortic aneurysm cases than among control patients (adjusted odds ratio, 5.97; P = .08), as was detectable IgM antibody (10% vs. 0%; P = .02). These findings suggest that infection with C. pneumoniae may play a role in the pathogenesis of abdominal aortic aneurysm; therefore, further research in this area is warranted.

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