Ceftriaxone Therapy for Staphylococcal Osteomyelitis: A Review | Zendy

B. Joseph Guglielmo | Zendy; Andrew D. Luber | Zendy; Domenic Paletta | Zendy; Richard A. Jacobs | Zendy

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Ceftriaxone Therapy for Staphylococcal Osteomyelitis: A Review

Author(s) -

B. Joseph Guglielmo,

Andrew D. Luber,

Domenic Paletta,

Richard A. Jacobs

Publication year - 2000

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/313620

Subject(s) - ceftriaxone , osteomyelitis , medicine , staphylococcus aureus , ambulatory , surgery , staphylococcal infections , antibiotics , microbiology and biotechnology , bacteria , biology , genetics

Ceftriaxone, although less active than standard antistaphylococcal agents, is potentially useful in the treatment of osteomyelitis. Thirty-one patients with osteomyelitis due to Staphylococcus aureus were identified, 22 of whom were treated with ceftriaxone and 9 with other agents. Of those patients treated with ceftriaxone, 17 were cured; all treatment failures were associated with chronic osteomyelitis and continued presence of necrotic bone or infected hardware. It is concluded that ceftriaxone is effective in the ambulatory treatment of S. aureus osteomyelitis.

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