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THE ACTIVATION OF SKIN GRAFTS
Author(s) -
Peyton Rous
Publication year - 1946
Publication title -
the journal of experimental medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 8.483
H-Index - 448
eISSN - 1540-9538
pISSN - 0022-1007
DOI - 10.1084/jem.83.5.383
Subject(s) - epidermis (zoology) , skin transplantation , pathology , biology , chemistry , medicine , anatomy , surgery
Rabbit skin rendered hyperplastic by various agents showed less tendency than normal skin to contract when sliced off, and when used for grafts it united with the bed more rapidly and was vascularized sooner. The stimulated epidermis proliferated practically at once, and abundantly, to cover adjacent raw surfaces. Also the donor area healed much more swiftly than usual and became infected less often. Certain grave limitations and hazards encountered during the experiments with hyperplastic grafts are considered.

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