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Fueling the fire: Src family kinases drive inflammation
Author(s) -
Klaus Ley
Publication year - 2014
Publication title -
the journal of experimental medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 8.483
H-Index - 448
eISSN - 1540-9538
pISSN - 0022-1007
DOI - 10.1084/jem.21110insight1
Subject(s) - lyn , inflammation , kinase , src family kinase , proto oncogene tyrosine protein kinase src , autoantibody , immunology , tyrosine protein kinase csk , arthritis , microbiology and biotechnology , medicine , biology , sh3 domain , antibody
![Figure][1] Insight from Klaus LeyThe Src family kinases (SFK) Hck, Fgr, and Lyn are the main SFKs in neutrophils and monocytes. In this issue, in a tour-de-force study of multiple disease models (autoantibody-induced arthritis [K/B×N serum-transfer], skin inflammation induced by

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