Open AccessLewis Dahl and the genetics of salt-induced hypertension
Author(s) -
Hema Bashyam
Publication year - 2007
Publication title -
the journal of experimental medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 8.483
H-Index - 448
eISSN - 1540-9538
pISSN - 0022-1007
DOI - 10.1084/jem.2047fta
Subject(s) - genetics , animal model , biology , essential hypertension , medicine , endocrinology , blood pressure
In the 1960s, Lewis Dahl bred two strains of rats that differed in their susceptibility to developing salt-induced hypertension. These animal models proved that hypertension induced by a high-salt diet is influenced by genetic background.
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