Open AccessMacrophages and nitric oxide: A deadly combination
Author(s) -
Jacqueline Ruttimann
Publication year - 2007
Publication title -
the journal of experimental medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 8.483
H-Index - 448
eISSN - 1540-9538
pISSN - 0022-1007
DOI - 10.1084/jem.20413fta
Subject(s) - nitric oxide , radical , immune system , microbiology and biotechnology , cell signaling , chemistry , macrophage , signal transduction , immunology , biology , biochemistry , in vitro , organic chemistry
In the late 1980s, Carl Nathan and colleagues pinpointed nitric oxide (NO) as a molecule that macrophages use to kill tumor cells. This discovery helped verify the role of radicals as signaling molecules in the immune system.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom