Open AccessBringing order to early B cell chaos
Author(s) -
Heather L. Van Epps
Publication year - 2006
Publication title -
the journal of experimental medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 8.483
H-Index - 448
eISSN - 1540-9538
pISSN - 0022-1007
DOI - 10.1084/jem.2036fta
Subject(s) - cell , biology , microbiology and biotechnology , order (exchange) , genetics , economics , finance
In the early 1990s, Richard (Randy) Hardy and colleagues divided B cell precursors into subpopulations—the Hardy fractions—based on the cells' expression of various cell surface proteins. This classification helped lay the groundwork for our present-day understanding of the molecular events that control early B cell development.
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