Macrophage activation unveiled
Author(s) -
Heather L. Van Epps
Publication year - 2005
Publication title -
the journal of experimental medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 8.483
H-Index - 448
eISSN - 1540-9538
pISSN - 0022-1007
DOI - 10.1084/jem.2027fta
Subject(s) - macrophage , bacteria , intracellular , intracellular parasite , biology , microbiology and biotechnology , immunology , biochemistry , genetics , in vitro
In the early 1960s, George Mackaness showed that macrophages from mice infected with intracellular bacteria could launch an indiscriminate attack against unrelated bacteria. Thus began an explosion of research on the biology of what Mackaness first termed "macrophage activation."
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