Open AccessHarry Goldblatt and the discovery of renin
Author(s) -
Heather L. Van Epps
Publication year - 2005
Publication title -
the journal of experimental medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 8.483
H-Index - 448
eISSN - 1540-9538
pISSN - 0022-1007
DOI - 10.1084/jem.2019fta
Subject(s) - renin–angiotensin system , medicine , blood pressure , endocrinology
In 1934, pathologist Harry Goldblatt established the first animal model of hypertension. This model provided researchers with the tools to delineate the renin-angiotensin system of blood pressure control and, eventually, to design enzyme inhibitors for the treatment of chronic hypertension.
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