Open AccessDiscovering lymphocyte subsets
Author(s) -
Heather L. Van Epps
Publication year - 2005
Publication title -
the journal of experimental medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 8.483
H-Index - 448
eISSN - 1540-9538
pISSN - 0022-1007
DOI - 10.1084/jem.2011fta
Subject(s) - miller , immunology , lymphocyte subsets , bone marrow , lymphocyte , biology , medicine , t cell , immune system , ecology
At a scientific meeting in 1968, Jacques Miller was accused of complicating immunology. He and others suggested that there was not one but two kinds of lymphocytes--one from the thymus and one from the bone marrow. In a pair of groundbreaking articles published in the Journal of Experimental Medicine in 1968, Miller and his student Graham Mitchell proved that two subsets of lymphocytes did exist and identified which subset mediated antibody responses.
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