Open AccessLost in translation
Author(s) -
Mitch Leslie
Publication year - 2005
Publication title -
the journal of cell biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.414
H-Index - 380
eISSN - 1540-8140
pISSN - 0021-9525
DOI - 10.1083/jcb1703fta1
Subject(s) - endoplasmic reticulum , biology , secretion , translation (biology) , microbiology and biotechnology , chromosomal translocation , mechanism (biology) , computational biology , genetics , biochemistry , gene , messenger rna , philosophy , epistemology
It was cell biology's version of the ship in the bottle. How do proteins a cell intends to secrete end up in the endoplasmic reticulum? Winkling out the details of the translocation mechanism that spirits these proteins into the ER required more than 20 years and earned Gunter Blobel of Rockefeller
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