Open AccessEndothelial tight junctions form the blood–brain barrier
Author(s) -
William Wells,
Laura Bonetta
Publication year - 2005
Publication title -
the journal of cell biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.414
H-Index - 380
eISSN - 1540-8140
pISSN - 0021-9525
DOI - 10.1083/jcb1693fta1
Subject(s) - biology , tight junction , blood–brain barrier , microbiology and biotechnology , biophysics , neuroscience , central nervous system
The concept of a barrier between blood vessels and the brain and spinal cord had existed since the late 1800s, when immunologist Paul Ehrlich found that intravenously administered dyes failed to stain certain regions of the brain, whereas other body tissues were stained. Ehrlich thought the dyes did
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