Open AccessOne protein, two pools
Author(s) -
Rabiya S. Tuma
Publication year - 2004
Publication title -
the journal of cell biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.414
H-Index - 380
eISSN - 1540-8140
pISSN - 0021-9525
DOI - 10.1083/jcb1672iti2
Subject(s) - biology , intracellular , cytoplasm , microbiology and biotechnology , vertebrate , gene , wnt signaling pathway , cover (algebra) , genetics , signal transduction , evolutionary biology , computational biology , mechanical engineering , engineering
The cytoplasmic protein β-catenin is essential for both intercellular adhesion and intracellular Wnt signaling. Invertebrates have multiple genes to cover the multiple functions, but on [page 339][1] Gottardi and Gumbiner propose that vertebrate cells make do with one gene by maintaining different
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