Open AccessKinase cascades are binary to the bone
Author(s) -
Alan W. Dove
Publication year - 2004
Publication title -
the journal of cell biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.414
H-Index - 380
eISSN - 1540-8140
pISSN - 0021-9525
DOI - 10.1083/jcb1643iti3
Subject(s) - biology , microbiology and biotechnology , computational biology , kinase , genetics
![Graphic][1] MAPK signaling is all or nothing. Like electronic relays, many biological signaling pathways are bistable, able to turn “on” or “off” in response to a stimulus, but unstable in intermediate positions. The conventional view is that bistable cellular signaling
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