Open AccessPulling to the protease
Author(s) -
William A. Wells
Publication year - 2003
Publication title -
the journal of cell biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.414
H-Index - 380
eISSN - 1540-8140
pISSN - 0021-9525
DOI - 10.1083/jcb1626rr5
Subject(s) - proteases , biology , protease , proteasome , peptide hydrolases , microbiology and biotechnology , enzyme , biochemistry
![Graphic][1] The unfolding force is constant over time.Sauer/ElsevierBefore destroying proteins, proteases such as bacterial ClpXP and the related eukaryotic proteasome must denature them. Jon Kenniston, Robert Sauer (MIT, Cambridge, MA), and colleagues now show that ClpX denatures
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