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Surviving heat through destruction
Author(s) -
William A. Wells
Publication year - 2003
Publication title -
the journal of cell biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.414
H-Index - 380
eISSN - 1540-8140
pISSN - 0021-9525
DOI - 10.1083/jcb1624rr3
Subject(s) - heat shock protein , biology , microbiology and biotechnology , heat shock , shock (circulatory) , ubiquitin , hsp60 , hsp70 , biochemistry , gene , medicine
![Graphic][1] Ubiquitination rescues heat-shocked lcb1 cells from death.Riezman/EMBOCanonical heat shock proteins (Hsps) help fold proteins. So it is easy to presume that, when Hsps are compromised, heat shock does its damage by depleting the cell of functional, folded proteins. But

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