Open AccessLoss of Rb launches cell cycle
Author(s) -
Rabiya S. Tuma
Publication year - 2003
Publication title -
the journal of cell biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.414
H-Index - 380
eISSN - 1540-8140
pISSN - 0021-9525
DOI - 10.1083/jcb1623rr5
Subject(s) - biology , microbiology and biotechnology , cell cycle , cell , genetics
![][1] Rapid loss of Rb (right; open bars) in fibroblasts induces cell cycle entry.Jacks/MacmillanUnlike germline mutations, acute somatic loss of an important tumor suppressor gene is sufficient to push quiescent cells into the cell cycle, according to Julien Sage, Abigail Miller
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom