Open AccessMS as a disease of immaturity
Author(s) -
William A. Wells
Publication year - 2002
Publication title -
the journal of cell biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.414
H-Index - 380
eISSN - 1540-8140
pISSN - 0021-9525
DOI - 10.1083/jcb1591rr4
Subject(s) - biology , myelin , multiple sclerosis , myelin sheath , oligodendrocyte , neuroscience , microbiology and biotechnology , immunology , central nervous system
![Graphic][1] Turning on Notch (right) inhibits oligodendrocyte maturation.John/MacmillanMultiple sclerosis (MS) lesions are characterized by loss of myelin, the insulating coat that surrounds axons. This is despite an abundance of the myelin-supplying glial cells called
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom