Open AccessA flipping permease
Author(s) -
William A. Wells
Publication year - 2002
Publication title -
the journal of cell biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.414
H-Index - 380
eISSN - 1540-8140
pISSN - 0021-9525
DOI - 10.1083/jcb1575rr1
Subject(s) - biology , permease , computational biology , microbiology and biotechnology , biophysics , biochemistry , transporter , gene
![Graphic][1] LacY (top) can flip orientations when deprived of a lipid (bottom).Dowhan/EMBOLipid bilayers should be a no-flipping zone for integral membrane proteins, with the hydrophobicity blocking any cross-membrane excursions. But now Mikhail Bogdanov, Phillip Heacock, and
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