Open AccessTurn-ons for axons
Author(s) -
Alan W. Dove
Publication year - 2002
Publication title -
the journal of cell biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.414
H-Index - 380
eISSN - 1540-8140
pISSN - 0021-9525
DOI - 10.1083/jcb1574iti1
Subject(s) - biology , low affinity nerve growth factor receptor , neuroscience , receptor , myelin , axon , neurotrophin , microbiology and biotechnology , myelin associated glycoprotein , glycoprotein , myelin sheath , central nervous system , genetics
![][1] Growth-blocking MAG (green) binds to the neurotrophin receptor p75NTR (red).When adult neurons are injured, myelin-associated glycoprotein (MAG) triggers signals to block the regrowth of axons, a process that is intensely frustrating to patients and researchers hoping to
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