Open AccessSurviving in low oxygen
Author(s) -
William Wells
Publication year - 2001
Publication title -
the journal of cell biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.414
H-Index - 380
eISSN - 1540-8140
pISSN - 0021-9525
DOI - 10.1083/jcb1555rr4
Subject(s) - biology , transcription factor , hypoxia (environmental) , oxygen , microbiology and biotechnology , genetics , gene , chemistry , organic chemistry
![][1] HIF-1α prevents cell death despite hypoxia (red) in a wild-type tibia.Johnson/CSHRandall Johnson (University of California, San Diego, CA) and colleagues have found that cells need a particular transcription factor to survive in the hypoxic interior of developing bones.
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