Open AccessFail-safe replication
Author(s) -
Tabitha M. Powledge
Publication year - 2001
Publication title -
the journal of cell biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.414
H-Index - 380
eISSN - 1540-8140
pISSN - 0021-9525
DOI - 10.1083/jcb1542rr1
Subject(s) - biology , dna replication , origin recognition complex , control of chromosome duplication , replication (statistics) , cell cycle , dna re replication , microbiology and biotechnology , dna , pre replication complex , genetics , licensing factor , eukaryotic dna replication , computational biology , cell , virology
![][1] Only yeast cells lacking all three regulation mechanisms (right) rereplicate their DNA.Li/MacmillanHow does the cell ensure that its DNA is replicated once and only once in every cell cycle? Replication takes place at many sites and must be regulated separately at each one
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