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By tissue culture methods and with the use of phase contrast, interference color contrast, and time-lapse cinematographic equipment, the activity of a cytoplasmic organoid, termed the microkinetosphere, has been followed and correlated with pinocytosis. A transformation of several microkinetospheres by coherence and coalescence into the solitary VP satellite was observed in cells undergoing pinocytosis in serum nutrients. A correlation of both of these structures to cytoplasmic organoids described by others, notably with the electron microscope, and a hypothesis on the nature of the microkinetosphere and its transformation was presented.

the journal of cell biology/the journal of cell biology

MICROKINETOSPHERES AND VP SATELLITES OF PINOCYTIC CELLS OBSERVED IN TISSUE CULTURES OF GEY'S STRAIN HELA WITH PHASE CONTRAST CINEMATOGRAPHIC TECHNIQUES