Open AccessGlycolytic cancer cells splice their way out of trouble
Author(s) -
Caitlin Sedwick
Publication year - 2015
Publication title -
the journal of cell biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.414
H-Index - 380
eISSN - 1540-8140
pISSN - 0021-9525
DOI - 10.1083/jcb.2107if
Subject(s) - biology , splice , alternative splicing , rna splicing , glycolysis , cancer cell , phenotype , microbiology and biotechnology , cancer , cancer research , genetics , computational biology , gene , biochemistry , rna , metabolism , exon
Cancer cells’ glycolytic phenotype drives alternative splicing of the proapoptotic protein Bnip3, producing a splice variant that protects against death.
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