Open AccessRab27a builds a platform for HIV-1
Author(s) -
Ben Short
Publication year - 2015
Publication title -
the journal of cell biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.414
H-Index - 380
eISSN - 1540-8140
pISSN - 0021-9525
DOI - 10.1083/jcb.2093iti3
Subject(s) - endosome , biology , human immunodeficiency virus (hiv) , microbiology and biotechnology , replication (statistics) , virology , computational biology , intracellular
![Figure][1] Compared with a control T cell (left), knocking down Rab27a blocks the delivery of late endosomes (red) to the plasma membrane, inhibiting the recruitment of Pr55Gag (green) to HIV-1 assembly sites.The endosomal trafficking protein Rab27a supports HIV-1 replication by
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