Open AccessHistone shortages hold back replication forks
Author(s) -
Mitch Leslie
Publication year - 2013
Publication title -
the journal of cell biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.414
H-Index - 380
eISSN - 1540-8140
pISSN - 0021-9525
DOI - 10.1083/jcb.2041iti2
Subject(s) - biology , histone , replication (statistics) , dna replication , microbiology and biotechnology , nucleosome , genetics , dna , virology
![Figure][1] In a cell low on histones, nucleosomes haven’t reformed behind a replication fork (inset).Much as an automobile assembly line slows if engines are in short supply, DNA replication slackens if the cell is low on new histones, [Mejlvang et al.][2] reveal.To replicate their
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