Open AccessPrion puts yeast cells under arrest
Author(s) -
Ben Short
Publication year - 2012
Publication title -
the journal of cell biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.414
H-Index - 380
eISSN - 1540-8140
pISSN - 0021-9525
DOI - 10.1083/jcb.1973iti2
Subject(s) - biology , mitosis , yeast , cytoplasm , microbiology and biotechnology , spindle pole body , component (thermodynamics) , organelle , saccharomyces cerevisiae , fungal prion , spindle apparatus , genetics , cell division , cell , physics , thermodynamics
![Figure][1] The SPB component Spc42 (green) is sequestered into cytoplasmic deposits of misfolded Rnq1 (red).Overexpression of a yeast prion protein prevents cells from undergoing mitosis by sequestering a key spindle pole body component, [Treusch and Lindquist][2] report.The prion
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