Open AccessPeptides prompt prions
Author(s) -
Ruth Williams
Publication year - 2007
Publication title -
the journal of cell biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.414
H-Index - 380
eISSN - 1540-8140
pISSN - 0021-9525
DOI - 10.1083/jcb.1775rr3
Subject(s) - biology , peptide , protein structure , computational biology , biochemistry
Short primary peptide structure drives the nucleation and self-perpetuation of prions, report Peter Tessier and Susan Lindquist (HHMI, Cambridge, MA).Prions self-perpetuate by binding their normal protein counterparts and inducing them to fold into the same abnormal conformation. Previous studies
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