A SMALL PARTICULATE COMPONENT OF THE CYTOPLASM | Zendy

George E. Palade | Zendy

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A SMALL PARTICULATE COMPONENT OF THE CYTOPLASM

Author(s) -

George E. Palade

Publication year - 1955

Publication title -

the journal of cell biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.414

H-Index - 380

eISSN - 1540-8140

pISSN - 0021-9525

DOI - 10.1083/jcb.1.1.59

Subject(s) - cytoplasm , endoplasmic reticulum , biology , ground substance , microbiology and biotechnology , component (thermodynamics) , cell , cell type , biochemistry , genetics , physics , connective tissue , thermodynamics

A particulate component of small dimensions (100 to 150 A) and high density is described in the ground substance of the cytoplasm of mammalian and avian cells. In many cell types that seem to have in common a high degree of differentiation, the new component is preferentially associated with the membrane of the endoplasmic reticulum; whereas in other cell types, characterized by rapid proliferation, it occurs more or less freely distributed in the ground substance of the cytoplasm. In the Discussion an attempt is made to integrate the observations presented in this paper with the already available cytological, histochemical, and cytochemical information.

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