Open AccessBiliary‐intestinal bypass in the treatment of obesity: long term follow up
Author(s) -
Boman Lars,
Domellöf Lennart
Publication year - 1998
Publication title -
european journal of surgery
Language(s) - English
Resource type - Journals
eISSN - 1741-9271
pISSN - 1102-4151
DOI - 10.1080/110241598750005129
Subject(s) - medicine , jejunoileal bypass , triglyceride , gastroenterology , gallbladder , body mass index , surgery , diabetes mellitus , obesity , blood lipids , renal function , retrospective cohort study , short bowel syndrome , cholesterol , weight loss , endocrinology , morbid obesity , parenteral nutrition
Objective: To evaluate the long term outcome after biliary‐intestinal bypass for morbid obesity. Design: Retrospective study. Setting: County hospital, Sweden. Subjects: 120 consecutive patients operated on between 1977 and 1990. Interventions: A variation of jejunoileal bypass in which the excluded bowel was anastomosed to the gallbladder. Main outcome measures: Weight, concentrations of blood lipids and glucose in blood, results of liver function tests, reversal rates, and complications. Results: The mean body mass index was reduced by 39% (from 42 kg/m 2 to 26 kg/m 2 ), serum cholesterol and triglyceride concentrations by more than 30%, and fasting blood glucose concentrations by 11%. There were no cases of irreversible hepatic failure, diabetes, deaths related to the operation, or progressive renal failure. The incidence of renal calculi increased by a ratio 2.3. The reversal rate/year was 2% ( n = 20). Conclusion: We conclude that biliary‐intestinal bypass may be used to treat cases of obesity associated with seriously high blood lipid concentrations and where gastric restrictive operations are less suitable. Copyright © 1998 Taylor and Francis Ltd.