Open AccessEfficacy of subcutaneous and topical local anaesthesia for pain relief after resection of malignant breast tumours
Author(s) -
Pettersson Nils,
Perbeck Leif,
Hahn Robert G.
Publication year - 2001
Publication title -
european journal of surgery
Language(s) - English
Resource type - Journals
eISSN - 1741-9271
pISSN - 1102-4151
DOI - 10.1080/11024150152717652
Subject(s) - medicine , prilocaine , morphine , anesthesia , visual analogue scale , bupivacaine , local anesthetic , surgery , infiltration (hvac) , analgesic , local anaesthetic , local anesthesia , breast cancer , cancer , physics , thermodynamics
Objective: Infiltration and topical application of local anaesthetics close to the surgical wound may be used to prevent postoperative pain. We evaluated the efficacy of these treatments after breast surgery for cancer. Design: Double‐blind randomised trial with two treatment groups and one control group. Setting: University hospital, Sweden. Interventions: Patients were allocated to treatment with bupivacaine infiltration ( n = 29), topical application of lignocaine/prilocaine ( n = 31), or no local treatment ( n = 30). Main outcome measures: Difference and time related patterns in pain scores measured on a visual analogue scale (VAS), and morphine consumption. Results. None of the local anaesthetics significantly reduced the VAS score or morphine consumption. However, fewer patients in the anaesthetic groups had high VAS scores than controls, the 75 th centile for the mean score after operation being 2.7, 2.0 and 2.1 for the controls, infiltration, and topical anaesthetic groups, respectively. The controls had higher scores from 6 hours postoperatively onwards. The corresponding median morphine consumption was 24.5, 18.5, and 16.2 mg. Conclusions. Local anaesthesia slightly reduced the overall pain scores and the morphine consumption, but was of potential clinical value only in the patients who had the highest pain scores. Copyright © 2001 Taylor and Francis Ltd.