Open AccessThe involvement of CD14 in the activation of human monocytes by peptidoglycan monomers
Author(s) -
Damir Muhvić,
Volker T. ElSamalouti,
HansDieter Flad,
Biserka RadoševićStašić,
Daniel Rukavina
Publication year - 2001
Publication title -
mediators of inflammation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.37
H-Index - 97
eISSN - 1466-1861
pISSN - 0962-9351
DOI - 10.1080/09629350123956
Subject(s) - monokine , peptidoglycan , cd14 , lipopolysaccharide , tumor necrosis factor alpha , monocyte , peripheral blood mononuclear cell , biology , cytokine , microbiology and biotechnology , chemistry , immunology , interleukin , receptor , biochemistry , in vitro , cell wall
Cell-wall components of Gram-positive and Gram-negative bacteria induce the production of cytokines in human peripheral blood mononuclear cells. These cytokines are the main mediators of local or systemic inflammatory reaction that can contribute to the development of innate immunity.
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