Open AccessEffects of fluticasone propionate inhalation on levels of arachidonic acid metabolites in patients with chronic obstructive pulmonary disease
Author(s) -
Gert T. Verhoeven,
Ingrid M. Garrelds,
Henk C. Hoogsteden,
Freek J. Zijlstra
Publication year - 2001
Publication title -
mediators of inflammation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.37
H-Index - 97
eISSN - 1466-1861
pISSN - 0962-9351
DOI - 10.1080/09629350123056
Subject(s) - fluticasone propionate , bronchoalveolar lavage , medicine , inhalation , copd , placebo , gastroenterology , asthma , arachidonic acid , fluticasone , bronchial hyperresponsiveness , asymptomatic , immunology , endocrinology , lung , respiratory disease , anesthesia , pathology , chemistry , biochemistry , enzyme , alternative medicine
In smoking COPD patients the bronchoalveolar lavage (BAL) fluid contains high numbers of inflammatory cells. These cells might produce arachidonic acid (AA) metabolites, which contribute to inflammation and an increased bronchomotor tone.
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