Open AccessThe glycosylation stoichiometry of EWS species in neuronal cells
Author(s) -
Kazuo Kamemura,
Hiromi Abe
Publication year - 2016
Publication title -
bioscience biotechnology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.509
H-Index - 116
eISSN - 1347-6947
pISSN - 0916-8451
DOI - 10.1080/09168451.2016.1230004
Subject(s) - glycosylation , stoichiometry , computational biology , biology , neuroscience , chemistry , evolutionary biology , biochemistry , organic chemistry
Although Ewing sarcoma protein (EWS) is known to be glycosylated by O-linked β-N-acetylglucosamine (O-GlcNAc), the dynamics and stoichiometry of its glycosylation remain obscure. Here, we report a dynamic change in the glycosylation stoichiometry of EWS species during neuronal differentiation of embryonic carcinoma P19 cells. Our findings suggest that O-GlcNAc glycosylation participates in the regulation of EWS functions in neuronal cells.
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