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Cytotoxicity of CdSe-based quantum dots incorporated in glass nanoparticles evaluated using human keratinocyte HaCaT cells
Author(s) -
Masanori Ando,
Masanori Horie,
Yoko Ogawa,
Yoshihisa Hagihara,
Norio Murase,
Yasushi Shigeri
Publication year - 2016
Publication title -
bioscience biotechnology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.509
H-Index - 116
eISSN - 1347-6947
pISSN - 0916-8451
DOI - 10.1080/09168451.2015.1069702
Subject(s) - hacat , cytotoxicity , quantum dot , leakage (economics) , nanoparticle , materials science , reagent , nanotechnology , polymer , fluorescence , chemistry , in vitro , organic chemistry , composite material , biochemistry , physics , optics , economics , macroeconomics
CdSe quantum dots (QDs) are potential fluorescent reagents, but leakage of Cd and Se often induces cytotoxicity. Here we prepared CdSe-based QDs with glass to reduce their leakage and examined their cytotoxicity using keratinocyte cells. The cytotoxicity of the QDs with glass was obviously lower than that of the commercial QDs with polymer, suggesting their safety for biological applications.

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