Population dynamics of flaviviruses revealed by molecular phylogenies. | Zendy

Paolo Marinho de Andrade Zanotto | Zendy; Ernest A. Gould | Zendy; George F. Gao | Zendy; Paul Harvey | Zendy; Edward C. Holmes | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Population dynamics of flaviviruses revealed by molecular phylogenies.

Author(s) -

Paolo Marinho de Andrade Zanotto,

Ernest A. Gould,

George F. Gao,

Paul Harvey,

Edward C. Holmes

Publication year - 1996

Publication title -

proceedings of the national academy of sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.011

H-Index - 771

eISSN - 1091-6490

pISSN - 0027-8424

DOI - 10.1073/pnas.93.2.548

Subject(s) - biology , phylogenetic tree , biological dispersal , evolutionary biology , phylogenetics , viral phylodynamics , population , genetics , virology , gene , demography , sociology

The phylogeny of 123 complete envelope gene sequences was reconstructed in order to understand the evolution of tick- and mosquito-borne flaviviruses. An analysis of phylogenetic tree structure reveals a continual and asymmetric branching process in the tick-borne flaviviruses, compared with an explosive radiation in the last 200 years in viruses transmitted by mosquitoes. The distinction between these two viral groups probably reflects differences in modes of dispersal, propagation, and changes in the size of host populations. The most serious implication of this work is that growing human populations are being exposed to an expanding range of increasingly diverse viral strains.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research