Encoded reaction cassette for the highly sensitive detection of the making and breaking of chemical bonds.
Author(s) -
Hicham Fenniri,
Kim D. Janda,
Richard A. Lerner
Publication year - 1995
Publication title -
proceedings of the national academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.92.6.2278
Subject(s) - reagent , combinatorial chemistry , computer science , decoding methods , chemistry , chemical reaction , nanotechnology , materials science , organic chemistry , algorithm
A reaction cassette has been designed for the highly sensitive detection of the making and breaking of chemical bonds. The system is envisioned as a companion device to be used in the search for antibody and other novel catalysts. The cassette also may have important clinical applications in the design of diagnostic reagents. In its fully encoded format, this methodology is capable of both detecting and decoding chemical events.
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