Open AccessThe retroviral oncogene qin belongs to the transcription factor family that includes the homeotic gene fork head.
Author(s) -
Jian Li,
Peter K. Vogt
Publication year - 1993
Publication title -
proceedings of the national academy of sciences of the united states of america
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.90.10.4490
Subject(s) - homeotic gene , fork (system call) , biology , gene , transcription factor , genetics , head (geology) , computer science , operating system , paleontology
Avian sarcoma virus 31 contains an oncogene that we have named qin. qin codes for a nuclear protein, Qin, that is a member of the HNF-3/fork head family of transcriptional regulators. Within this family Qin is particularly closely related to rat brain factor 1 (BF-1), a telencephalon-specific gene presumed to play an important role in the development of the mammalian brain.