Open AccessSearch for cellular phosphorylation products of D-allose.
Author(s) -
Donna Ullrey,
H. M. Kalckar
Publication year - 1991
Publication title -
proceedings of the national academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.88.4.1504
Subject(s) - hexose , biochemistry , chemistry , hamster , phosphorylation , regulator , phosphate , biology , microbiology and biotechnology , enzyme , gene
The all-cis hexose D-allose, fed to hamster fibroblast cultures over 14-20 hr, brings about a striking down-regulation of hexose transport. This down-regulation by allose is inhibited by 2,4-dinitrophenol. By using D-[14C]allose and thin-layer chromatography, two types of products accumulated that have been identified as allose and allose phosphate. We suspect that allose phosphate might be the down-regulator.
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