Monoclonal antibodies specific for murine CD2 reveal its presence on B as well as T cells. | Zendy

H Yagita | Zendy; Takuro Nakamura | Zendy; Hajime Karasuyama | Zendy; Ko Okumura | Zendy

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Monoclonal antibodies specific for murine CD2 reveal its presence on B as well as T cells.

Author(s) -

H Yagita,

Takuro Nakamura,

Hajime Karasuyama,

Ko Okumura

Publication year - 1989

Publication title -

proceedings of the national academy of sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.011

H-Index - 771

eISSN - 1091-6490

pISSN - 0027-8424

DOI - 10.1073/pnas.86.2.645

Subject(s) - monoclonal antibody , microbiology and biotechnology , immunoprecipitation , immunofluorescence , antibody , complementary dna , biology , western blot , antigen , blot , gene , immunology , biochemistry

Monoclonal antibodies specific for the murine CD2 antigen were identified by an efficient screening method utilizing murine CD2 cDNA transfectants. An unexpected expression of CD2 on murine B cells was revealed by immunofluorescence and immunoprecipitation studies with these monoclonal antibodies and by RNA blot analysis for the murine CD2 transcript.

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