cricklet: A locus regulating a number of adult functions of Drosophila melanogaster | Zendy

Alan D. Shirras | Zendy; Mary Bownes | Zendy

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cricklet: A locus regulating a number of adult functions of Drosophila melanogaster

Author(s) -

Alan D. Shirras,

Mary Bownes

Publication year - 1989

Publication title -

proceedings of the national academy of sciences

Language(s) - English

Resource type - Journals

eISSN - 1091-6490

pISSN - 0027-8424

DOI - 10.1073/pnas.86.12.4559

Subject(s) - drosophila melanogaster , vitellogenesis , yolk , biology , mutant , juvenile hormone , locus (genetics) , larva , melanogaster , gene , microbiology and biotechnology , drosophilidae , genetics , medicine , endocrinology , hormone , embryo , oocyte , ecology , botany

During a screen for mutations in trans-acting genes regulating yolk protein synthesis inDrosophila melanogaster , we have isolated a mutant (cricklet,clt ) that is defective in yolk protein synthesis, histolysis of the larval fat body, vitellogenesis, and synthesis of larval serum protein 2 in the adult, larval synthesis occurring normally. Larval serum protein 2 was previously thought to be synthesized only in the third-instar larva. We suggest that theclt locus may encode a protein essential for mediating the response of adult tissues to juvenile hormone.

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