Open AccessNucleotide sequence of the yeast regulatory gene STE7 predicts a protein homologous to protein kinases.
Author(s) -
Michael A. Teague,
Deborah T. Chaleff,
Beverly Errede
Publication year - 1986
Publication title -
proceedings of the national academy of sciences of the united states of america
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.83.19.7371
Subject(s) - gene , biology , taf4 , genetics , saccharomyces cerevisiae , autophagy related protein 13 , homology (biology) , regulator gene , nucleic acid sequence , ddb1 , protein phosphorylation , protein kinase a , regulation of gene expression , kinase , gene expression , dna binding protein , transcription factor , promoter
The nucleotide sequence of the STE7 gene from Saccharomyces cerevisiae has been determined. It is one of several regulatory genes implicated in the control of cell-type-specific gene expression in yeast. The predicted amino acid sequence shows homology to several members of the protein kinase family. These results suggest protein phosphorylation may play a key role in regulation leading to cell-type specialization in yeast.