α-Amanitin resistance is developmentally regulated in carrot | Zendy

Letizia Pitto | Zendy; Fiorella Lo Schiavo | Zendy; M. Terzi | Zendy

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α-Amanitin resistance is developmentally regulated in carrot

Author(s) -

Letizia Pitto,

Fiorella Lo Schiavo,

M. Terzi

Publication year - 1985

Publication title -

proceedings of the national academy of sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.011

H-Index - 771

eISSN - 1091-6490

pISSN - 0027-8424

DOI - 10.1073/pnas.82.9.2799

Subject(s) - somatic cell , mutant , biology , mutation , microbiology and biotechnology , somatic fusion , biochemistry , gene

Carrot cells are capable of inactivating α-amanitin only in embryogenic conditions (regenerating cells and embryoids). Instead, the mutant line a3 is capable of inactivating the drug also in nonembryogenic conditions (vegetative growth). The mutation is dominant in somatic hybrids and is pleiotropic, allowing expression during vegetative growth of other embryonal functions. The inactivation of α-amanitin is due to the oxidative activity of tyrosinase.

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