Open Accessα-Amanitin resistance is developmentally regulated in carrot
Author(s) -
Letizia Pitto,
Fiorella Lo Schiavo,
Mario Terzi
Publication year - 1985
Publication title -
proceedings of the national academy of sciences of the united states of america
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.82.9.2799
Subject(s) - somatic cell , mutant , biology , mutation , microbiology and biotechnology , somatic fusion , biochemistry , gene
Carrot cells are capable of inactivating α-amanitin only in embryogenic conditions (regenerating cells and embryoids). Instead, the mutant line a3 is capable of inactivating the drug also in nonembryogenic conditions (vegetative growth). The mutation is dominant in somatic hybrids and is pleiotropic, allowing expression during vegetative growth of other embryonal functions. The inactivation of α-amanitin is due to the oxidative activity of tyrosinase.