Open AccessSpatial distribution of transcripts of the long repeated ETn sequence during early mouse embryogenesis.
Author(s) -
Philippe Brûlet,
Hubert Condamine,
François Jacob
Publication year - 1985
Publication title -
proceedings of the national academy of sciences of the united states of america
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.82.7.2054
Subject(s) - ectoderm , embryo , biology , in situ hybridization , embryogenesis , embryonic stem cell , induced pluripotent stem cell , rna , transposable element , microbiology and biotechnology , genetics , messenger rna , gene , genome
RNA X DNA in situ hybridization revealed a high level of ETn ("early transposon") transcripts in the pluripotent cell lineage of the 3.5- to 7.5-day mouse embryo. Some extra-embryonic ectoderm derivatives also show a high level of ETn transcripts at these stages. Older embryos (8.5 days and later) have a uniform low level of ETn transcripts.