Allelic inclusion in the pre-B-cell line 18-81. | Zendy

Matthias Wabl | Zendy; Gabriele BeckEngeser | Zendy; Peter D. Burrows | Zendy

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Allelic inclusion in the pre-B-cell line 18-81.

Author(s) -

Matthias Wabl,

Gabriele BeckEngeser,

Peter D. Burrows

Publication year - 1984

Publication title -

proceedings of the national academy of sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.011

H-Index - 771

eISSN - 1091-6490

pISSN - 0027-8424

DOI - 10.1073/pnas.81.3.867

Subject(s) - allelic exclusion , allele , biology , inclusion (mineral) , genetics , cell , cell culture , inclusion bodies , virology , microbiology and biotechnology , gene , t cell , chemistry , immune system , t cell receptor , mineralogy , escherichia coli

In an Abelson-virus-transformed mouse lymphoid cell line with pre-B-cell characteristics, a few cells continuously produce heavy chains from both homologs. Each chain has a different variable region. These cells thereby exhibit allelic inclusion rather than allelic exclusion.

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