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Fluctuation x-ray scattering from biological particles in frozen solution by using synchrotron radiation.
Author(s) -
Zvi Kam,
Manuel Koch,
J. Bordas
Publication year - 1981
Publication title -
proceedings of the national academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.78.6.3559
Subject(s) - synchrotron radiation , scattering , x ray , synchrotron , small angle x ray scattering , radiation , optics , anomalous scattering , materials science , physics , computational physics
Determination of the structure of biological particles, randomly oriented in solution, from spatial correlation analysis of fluctuations in x-ray scattering has recently been proposed. The feasibility of scattering fluctuation measurements was evaluated by using an x-ray synchrotron radiation camera to obtain the spatial correlation for a solution of tobacco mosaic virus along a line. The experimental system, analysis of data, and requirements for the determination of structures in solution are discussed using this example.

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