Photoisomerized bilirubin in blood from infants receiving phototherapy. | Zendy

Angelo A. Lamola | Zendy; W. E. Blumberg | Zendy; Richard E. McClead | Zendy; A.A. Fanaroff | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Photoisomerized bilirubin in blood from infants receiving phototherapy.

Author(s) -

Angelo A. Lamola,

W. E. Blumberg,

Richard E. McClead,

A.A. Fanaroff

Publication year - 1981

Publication title -

proceedings of the national academy of sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.011

H-Index - 771

eISSN - 1091-6490

pISSN - 0027-8424

DOI - 10.1073/pnas.78.3.1882

Subject(s) - bilirubin , pigment , blue light , solubility , fluorescence , chemistry , medicine , organic chemistry , optics , physics

A pigment different from (Z,Z)bilirubin-IX alpha was detected by fluorometric methods in blood specimens from newborn infants undergoing blue-light therapy for unconjugated hyperbilirubinemia; it was not detected in specimens from infants not under therapy. The phototherapy-associated pigment has fluorescence, solubility, and photochemical properties that are identical to those exhibited by what are thought to be configurational (Z leads to E) isomers of bilirubin. It is concluded that isomerized bilirubin in the blood of neonates under phototherapy can reach as high as 15% of the total.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research