Open AccessProduction of hybridomas secreting monoclonal antibodies to the human leukocyte interferons.
Author(s) -
Theophil Staehelin,
Brigitte Durrer,
Jörg Schmidt,
B. Takács,
John Stocker,
V. Miggiano,
C. Stähli,
Menachem Rubinstein,
Warren P. Levy,
Robert Hershberg,
Sidney Pestka
Publication year - 1981
Publication title -
proceedings of the national academy of sciences of the united states of america
Language(s) - English
Resource type - Journals
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.78.3.1848
Subject(s) - monoclonal antibody , interferon , biology , antibody , virology , immunology , monoclonal , microbiology and biotechnology
Thirteen monoclonal antibodies to human leukocyte interferon have been obtained. They exhibit different patterns of binding to purified leukocyte interferon species that are consistent with the structural multiplicity of the human leukocyte interferons. These antibodies will be useful as probes into the structure of the human leukocyte interferons, for their purification, and for rapid assay of leukocyte interferon.